Students often ask to be tested for “everything”. Sexually transmitted infections can be transmitted to the vagina, penis, skin, throat, blood stream, or colorectal mucosa through intimate contact. The most commonly diagnosed STIs in sexually active college students are chlamydia, human papilloma virus (HPV), genital herpes, and gonorrhea. We test for these infections, as well as for syphilis, Hepatitis B and C, and HIV/AIDS by blood, urine tests, swabs of the cervix, throat or rectal cultures, as indicated. Some of these tests have charges. Some of these infections are preventable by vaccination – this includes Hepatitis B and HPV. We urge all students to use condoms for contraception, and as an effective barrier against STIs.